I can't speak for the other skins, but I see quite a few refinements and changes between the CS Charmed and Vogue lines, particularly when I switch back to Charmed after wearing Vogue for a while...I look a little less defined overall in the Charmed.
That's only to be expected, Ann...since the Charmed line is semi transparent in order to allow you to adjust the skin tone with the Appearance sliders.
Nevertheless, I prefer Charmed to Vogue overall.