Is this possible.....

ok ran into a problem where a smoking animation I made using Avimation doesn't play right on male and female Av's, so had to make two seperate anims, is it possible to make a script that will ask when you equip the cig, which anim you would like to use and then start the standard smoking actions using said anims?

sure

Slightly more usefully - look up llDialog[/ulr] on the [url=http://secondlife.com/badgeo/wakka.php?wakka=HomePage]wiki[/url].

Although there are fancier ways to do it, given the ability people have to change shapes popping up a dialog box every time they attach it, asking if they're male or female then using the listen event to trigger the correct anim based on their reply works pretty well.