Hmmm, a couple of people warned me off AMD dual cores when I was building a new system in April. I'm told the dual cores *can* have problems in SL - plus SL doesn't support them anyway, so it only makes sense if you want to run SL on one core and one or more other 'hungry' programs on the other... I plumped for a FX57 for one machine and a 64-4000+ in the other, both very nice, though the FX is just that little bit faster

but probably not enough to really justify the extra cost.
What IS important with these cpus however is getting hold of low latency RAM, it makes a noticable difference to performance.
As far as SLi is concerned - who knows? My MB (DFI LanParty nF4 SLi-DR Expert) handles it, but given my results in 1.10 with a single card I'm not wasting money on another for SL!
What I
do know is that a BFG 7900GTX 512 which worked REALLY well in 1.9 is now suffering all sorts of problems. Moderate to severe fps reduction depending on location (accurately measured and verifiable), texture strobing, slow texture loading and general wierdness. Oh, and a dead stable system now crashes fairly regularly in SL!
Obviously on a PC built from scratch last month it has a) the latest offical drivers, b) no 'old' driver leftovers, c) a brand new clean XP SP2...
SL has been clean installed a couple of times too. So, a pretty high end syatem that used to work well in SL and doesn't any more.
I had these troubles in Preview (though not, strangely, the strobing textures) from when they crippled the vertex shaders, which were bug reported but sadly not fixed prior to release.
My feeling is that while some of the lower spec nVidias are OK in 1.10 - 6600s seem particularly trouble free - the higher end cards are having 'issues'. If I were bolting something together right now I think I'd shove a cheap 6600 in to use until (if) LL get their act together with the high end cards - if you want this machine mainly for SL that is.
I know it's not hugely encouraging, but those 512 cards are fairly expensive, I'm irritated enough at having bought one that no longer works acceptably, I'd hate you to shell out twice as much and have the same outcome.