how to arrange texture "quadrants" for animation?

i'm wanting to do some textures for animation using a simmilar method to furry blinking eyes. like when you look at the texture on those and notice 4 pairs of eyes, one in each corner of the image.

i understand the idea behind this and i know how to script it, but when it comes to photoshopping the eyes(or anything else), what's the trick to making sure they're all relatively in the same place?

i'm having trouble wording my question. basically, i'm afraid i won't be able to just eyeball the exact "center" of each quadrant of the image so that my eyes or whatever won't look all shifty weird when i flip through the offsets in sl. do you actually make a normal animated gif first, and then use some sort of plugin to splay the frames out onto a single texture so you know each frame is properly centered? what's the name of the trick/photoshop tool i'm looking for here?

If making a GIF is easy for you, you can use this tool to make it into an "animated" texture:

http://www.peregrinesalon.com/anim/

However, you can do it easily in Photoshop without a plugin.

Make a series of stills (or one still with layers, whichever works best for you) of the animation images you need. They should be scaled into a square of 128x128 or 256x256 pixels, depending on how many frames you need and the size of the final texture. That is, if the final texture is 512x512 and you have four frames, then each frame image will be 256x256.

Then make a new Photoshop document large enough to hold them all, and divide it up evenly using snap-to guides. Setting the rulers to "pixels" helps. If you have snap on, Photoshop will help out a bit by snapping the guide to the background's center.

Copy and paste the individual frames into thier respective spots, using the snap-to guides to get them aligned.

Voila!

hey jil been a while! thanks! that's just the type of thing i was looking for. i knew about the website tool, but what i want needs transparency (eyes were just the best example i could come up with), and the web tool was always kinda hit or miss with transparent images. i get what you're saying with the snap thing though. i'll do that ^^